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Overview

Lenovo ThinkPad P16s Gen 5 AMD Laptop, 16" IPS 60Hz, Ryzen AI 7 PRO 450 Processor, AMD Radeon 860M , 64GB, 2TB SSD

Lenovo ThinkPad P16s Gen 5 AMD Laptop, 16" IPS 60Hz, Ryzen AI 7 PRO 450, 64GB, 2TB SSD

Brand: Lenovo
Model: 21XG003DUS
Web Code: 20092327
Sold and shipped by | 3.9 seller rating (1,171 reviews)

Available for deliveryAvailable online only

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Warranty

Check with the manufacturer for details.

For Quebec residents: See the Availability Guarantee disclosure in the Specifications section below.

Unlock efficiency & innovation with Copilot+ PCs.Improve operational efficiency with Copilot+ PCs.16‑inch mobile workstation for engineers, designers & professionals

·Copilot+ PC powered by AMD Ryzen™ AI PRO for responsive, on‑device AI work

·Adaptable performance with scalable memory & graphics for demanding workflows

· MAINSTREAM MOBILE WORKSTATION POWER

The Lenovo ThinkPad P16s Gen 5 AMD brings mainstream workstation performance into a portable 16ʺ design, starting under 2kg / 4lbs. With AMD Ryzen™ AI PRO Series processing, a dedicated neural processing unit (NPU), and optional NVIDIA RTX PRO™ graphics, it easily handles AI‑supported workflows and professional applications without compromising mobility.

AMD RYZEN™ AI PRO PERFORMANCEBuilt For Real Workflows

Powered by AMD Ryzen™ AI PRO processors with built‑in AI acceleration, the ThinkPad P16s makes light work of complex tasks while bringing next‑generation AI productivity straight to the device. Everything stays fast, responsive, and efficient as you move through your day.

PRO-LEVEL GRAPHICS POWERDesigned for Demanding Creative Work

Choose graphics that fit how you work. Integrated AMD Radeon™ graphics support efficient day‑to‑day creation, while optional NVIDIA RTX PRO™ graphics accelerate rendering, visualization, and AI‑enabled tasks when workloads demand more.

PORTABLE MOBILE WORKHORSESerious Performance. Portable Design.

This redesigned 16ʺ workstation starts under 2kg / 4lbs, making high‑performance work easier to carry between office, home, and job sites. You get the capability you need — without committing to a desk. 

ON‑DEVICE AI WITH COPILOT+ EXPERIENCES

A dedicated AMD XDNA™ 2 NPU enables AI tasks to run directly on the device, helping everyday work feel faster and more responsive. With support for Copilot+ experiences, AI assistance runs locally to surface timely suggestions, streamline routine tasks, and launch instantly with a single key press.

High‑Impact Display Options

The 16ʺ workspace comes with multiple display options designed for clarity and comfort. Antiglare panels and Eyesafe® certified technology help reduce eye strain during long sessions, while OLED options deliver rich contrast and accurate colour when precision matters.

Next-Generation Memory Architecture

Advanced high-speed LPCAMM2 memory delivers higher bandwidth and smoother responsiveness as workloads grow. With support for large memory capacities, the system keeps complex files, simulations, and multitasking moving without constant slowdowns.

PCIe® Gen 5 Storage  

High‑speed PCIe® Gen 5 SSD support helps reduce load times and keeps large files moving quickly. From project launches to file transfers, storage performance stays out of your way — even when data demands increase.

ISV‑Certified Reliability  

Run CAD, BIM, and creative applications with confidence, backed by independent software vendor (ISV)* certifications from leading professional software providers. These certifications help ensure consistent behavior and dependable results across complex, day‑to‑day workflows.*See the complete list of ISV certifications

ENTERPRISE-GRADE SECURITY

ThinkShield security combines hardware‑based protections and system‑level safeguards to help protect data and identity. Discrete Trusted Platform Module (dTPM) and a self‑healing BIOS help secure critical information, while biometric login with the fingerprint reader or facial recognition with the optional IR camera keeps access protected from startup to sign‑off.

Advanced Connectivity  

Fast WiFi, optional 5G, and a port‑rich design — including built‑in RJ45 — make it easier to stay connected across offices, home workspaces, and job sites. Whether you’re docked or mobile, connectivity stays reliable and flexible.

All‑Day Power With Rapid Charging

Choose between 60WHr or 90WHr customer‑replaceable battery options designed to support long workdays, whether you’re in the office or out in the field. When it’s time to recharge, rapid‑charging support helps you get back up and running quickly, with a battery built for easy servicing over time.

Easy Upgrades & Scalable Serviceability

Designed with customer‑replaceable components — including the D‑cover, battery, keyboard, WWAN, SSD, USB‑C ports, and memory — the ThinkPad P16s is designed to scale alongside your needs and reduce total cost of ownership as workloads grow.

Smarter Collaboration Experience

Choose a 5MP RGB camera or a 5MP RGB, Infrared (IR), and CV camera with Human Presence Detection. Both options help you look clear and professional on calls, while built‑in privacy features, including the privacy shutter, keep you in control when meetings end.

Reliable Performance For AEC Projects

Handle large CAD drawings and BIM models with AMD Ryzen™ AI PRO processing built to manage complex datasets. Combined with support for high memory capacities, the system keeps navigation and design reviews responsive as projects grow in size and detail.

Media & Entertainment

Bring animation, visual effects, and editing workflows together with optional NVIDIA RTX PRO™ graphics tuned for creative workloads. Smooth playback and faster previews help creators refine scenes, iterate quickly, and stay focused from first cut to final output.

Healthcare & Life Sciences

Work with imaging, analysis, and research data in environments where protection matters. ThinkShield security helps safeguard sensitive information, supporting confident day‑to‑day workflows across labs, clinics, and mobile healthcare settings.

Automotive Design & Engineering

Support automotive design and engineering workflows with performance validated for professional software. ISV certification helps ensure reliable behavior across CAD, visualization, and simulation review as teams iterate across studio and engineering environments.

THINKPAD TOUGH

ThinkPad laptops are tested to rigorous MIL‑STD‑810H standards to help ensure dependable performance in demanding environments. Extensive testing, from extreme temperatures and pressure to vibration, dust, and humidity, helps deliver the durability businesses need, whether work happens in the field, on the road, or in challenging conditions.

CREDIBILITY & COLLABORATION

Our goal is to provide smarter technology that builds a brighter, more sustainable future for our customers, communities, and the planet. That's why we pursue industry leading labels and certifications that demonstrate our commitment to sustainability in product design. Together, we can build a smarter future for all.

    

For Quebec residents – Disclosure under the Consumer Protection Act

In compliance with Bill 29, Best Buy and third-party sellers on Best Buy Marketplace do not guarantee the availability of replacement parts, repair services, or maintenance information for any products. Coverage provided through any Best Buy Protection programs and applicable manufacturer warranties, if any, remain in place. Please contact the manufacturer directly for information about their availability guarantee.

Shipping Charges

Free standard shipping on all orders.

Processing Time

Most items ship within 2 business days after an order is placed*. Allow additional time for shipping to your address.
*Please note: If an item you ordered becomes unavailable, you'll be notified and a full refund will be processed within 2 business days.

Shipping Area Restrictions

Shipping is not available in the following areas*:
  • No restrictions in Canada
*Please note: Shipping area restrictions may vary for large items. If an item can't be shipped to your address, we'll let you know during the checkout process.
Product Category
Computers (laptops and desktops)
Return/Exchange Period
30 days
Condition
Opened